Dirty Bomb minimises during play

When I play DB my game will minimise during gameplay. I have an X34a Predator 3440x1440 monitor but play 2560 x 1440 Fullscreen. I have noticed that my mouse pointer will disappear from the right side of the screen which causes the minimisation issue, but never from the left side of the screen. I have posted a copy of my video settings. Any ideas?